参考文献

1.曹雪涛．免疫学前言进展．北京：人民卫生出版社，2014.

2.曹雪涛．医学免疫学．北京：人民卫生出版社，2016.

3.王大永，徐翔，孙立倩，等．亚低温治疗对脑出血大鼠TLR4/NF-κB介导的神经炎症反应的影响．神经解剖学杂志，2015，31（3）：309-314.

4.王亚楠，张勇，王宁，等．亚低温对大鼠脑损伤后TNF-α、IL-1β及NF-κB表达的影响．中国免疫学杂志，2014，30（5）：618-622.

5.陈亚妮，王延琦，万红，等．高原高寒环境对人体功能的影响及预防．职业与健康，2014，30（10）：1409-1412.

6.孙嵘，马琼，杜丽，等．毫米波辐照所致急性应激对小鼠细胞因子和Th1/Th2免疫平衡的影响．解放军医学杂志，2013，38（10）：859-863.

7.郭曦尧，尹玉伟，茆安婷，等．铅暴露对鲫鱼抗氧化及免疫能力的影响．中国兽医科学，2018，48（2）：222-227.

8.李玄，王锐，尹大强．饮用水汞暴露对小鼠免疫系统的毒性．环境化学，2014，33（9）：1427-1432.

9.许智鸿，王冰焱，王雅华，等．慢性砷暴露对大鼠组织与免疫细胞功能的影响．福建医科大学学报，2016，50（1）：6-10.

10.郭长江，顾景范．植物化学物及其生物学作用．营养学报，2010，32（6）：521-523.

11.高蔚娜，韦京豫，郭长江，等．不同产地原料蜂胶对衰老小鼠体液免疫功能影响的比较研究．中国免疫学杂志，2013，29（12）：1262-1264.

12.石塔拉，高蔚娜，郭长江．膳食成分与肠道菌群相互作用．营养学报，2016，38（6）：530-535.

13.Knez W，Girard O，Racinais S，et al. Does living and working in a hot environment induce clinically relevant changes in immune function and voluntary force production capacity. Industrial health，2014，52（3）：235-239.

14.Sturrock A，Woller D，Paine R. Hypoxia Suppresses Innate Immune Function in Primary Murine Alveolar Epithelial Cells Through Effects On The Redox-Sensitive Factor. Am J Resp Crit Care，2016，193（5）：152-161.

15.Kim S，Choe JH，Lee GJ，et al. Ionizing Radiation Induces Innate Immune Responses in Macrophages by Generation of Mitochondrial Reactive Oxygen Species. Radiation research，2017，187（1）：32-41.

16.Perween S，Kumar K，Chandramoni，et al. Effect of feeding different dietary levels of energy and protein on growth performance and immune status of Vanaraja chicken in the tropic. Veterinary world，2016，9（8）：893-899.

17.Jiao X，Yang K，An Y，et al. Alleviation of lead-induced oxidative stress and immune damage by selenium in chicken bursa of Fabricius. Environmental Science and Pollution Research International，2017，24（8）：7555-7564.

18.Kasten-Jolly J，Lawrence DA. Sex-specific effects of developmental lead exposure on the immuneneuroendocrine network. Toxicol Appl Pharmacol，2017，334（1）：142-157.

19.Hornsby E，Pfeffer PE，Laranjo N，et al. Vitamin D supplementation during pregnancy：Effect on the neonatal immune system in a randomized controlled trial. The Journal of Allergy and Clinical Immunology，2018，141（1）：269-278.

20.Min YN，Niu ZY，Sun TT，et al. Vitamin E and vitamin C supplementation improves antioxidant status and immune function in oxidative-stressed breeder roosters by up-regulating expression of GSH-Px gene. Poultry science，2018，97（4）：1238-1244.

21.Kloubert V，Blaabjerg K，Dalgaard TS，et al. Influence of zinc supplementation on immune parameters in weaned pigs. J Trace Elem Med Biol，2018，49（9）：231-240.

22.Zheng L，Feng L，Jiang WD，et al. Selenium deficiency impaired immune function of the immune organs in young grass carp（Ctenopharyngodon idella）．Fish Shellfish Immunol，2018，77（3）：53-70.

23.Patel S. Phytochemicals for taming agitated immune-endocrine-neural axis. Biomed Pharmacother，2017，91（7）：767-775.

24.Zhuo X，Sun H，Wang S，et al. Ginseng Stem-and-Leaf Saponin（GSLS）-Enhanced Protective Immune Responses Induced by Toxoplasma gondii Heat Shocked Protein 70（HSP70）Against Toxoplasmosis in Mice.The Journal of Parasitology，2017，103（1）：111-117.

25.Ahlberg V，Hjertner B，Wallgren P，et al. Innate immune responses induced by the saponin adjuvant Matrix-M in specific pathogen free pigs. Veterinary Research，2017，48（1）：30-39.

26.Choi JH，Chung MJ，Jeong DY，et al. Immunostimulatory activity of isoflavone-glycosides and ethanol extract from a fermented soybean product in human primary immune cells. Journal of Medicinal Food，2014，17（10）：1113-1121.

27.Bhardwaj J，Chaudhary N，Seo HJ，et al. Immunomodulatory effect of tea saponin in immune T-cells and T-lymphoma cells via regulation of Th1，Th2 immune response and MAPK/ERK2 signaling pathway.Immunopharmacology and Immunotoxicology，2014，36（3）：202-210.

28.Tang C，Sun J，Zhou B，et al. Effects of polysaccharides from purple sweet potatoes on immune response and gut microbiota composition in normal and cyclophosphamide treated mice. Food Funct，2018，9（2）：937-950.

29.Pan GF，Xie ZW，Huang SX，et al. Immune-enhancing effects of polysaccharides extracted from Lilium Lancifolium Thunb. International Immunopharmacology，2017，52（11）：119-126.

30.Oh MJ，Choi HD，Ha SK，et al. Immunomodulatory effects of polysaccharide fraction isolated from Fagopyrum esculentum on innate immune system. Biochemical and Biophysical Research Communications，2018，496（4）：1210-1216.

31.Jia XJ，Liang YE，Zhang C，et al. Polysaccharide PRM3 from Rhynchosia minima root enhances immune function through TLR4-NF-kappa B pathway. Bba-Gen Subjects，2018，1862（8）：1751-1759.

32.Iurescia S，Fioretti D，Rinaldi M. Nucleic Acid Sensing Machinery：Targeting Innate Immune System for Cancer Therapy. Recent Patents on Anti-Cancer Drug Discovery，2018，13（1）：2-17.

33.Ori D，Murase M，Kawai T. Cytosolic nucleic acid sensors and innate immune regulation. Int Rev Immunol，2017，36（2）：74-88.

34.Miyake K，Shibata T，Ohto U，et al. Emerging roles of the processing of nucleic acids and Toll-like receptors in innate immune responses to nucleic acids. J Leukocyte Biol，2017，101（1）：135-142.

35.Yamashiro LH，Oliveira SC，Bafica A. Innate immune sensing of nucleic acids from mycobacteria. Microbes Infect，2014，16（12）：991-997.